Kimera Labs

Histidine

Compound Summary

Antioxidant, fights the free radicals that cause wrinkles. Anti-inflammatory properties that soothe skin.

Results of Histidine (His) Supplementation in a Case of Severe Nummular Eczema (NE)

l-Histidine Supplementation in Adults and Young Children with Atopic Dermatitis (Eczema)

Antioxidant characteristics of L-histidine

Histidine is an essential amino acid that our bodies cannot produce on their own, making it crucial to obtain through our diet or supplements. Histidine exhibits antioxidant and anti-inflammatory properties, which are crucial for maintaining skin health. It helps neutralize free radicals, reducing oxidative stress and preventing damage to skin cells. Additionally, histidine can modulate inflammatory responses. Histidine plays a role in maintaining the integrity of the skin barrier. It helps regulate the pH balance of the skin, which is essential for optimal barrier function. Additionally, histidine is involved in the regulation of skin hydration. It helps maintain the skin’s natural moisture balance by supporting the production of natural moisturizing factors (NMFs), such as urea and pyrrolidone carboxylic acid. By promoting proper moisture retention, histidine contributes to a hydrated and supple complexion. [15]

Moro, J., et al., Histidine: A Systematic Review on Metabolism and Physiological Effects in Human and Different Animal Species. Nutrients, 2020. 12(5).