Purified Mesenchymal Stem Cell (MSC) Exosomes
Pharmaceutical Grade MSC Exosomes for Clinical Research
Purified Mesenchymal Stem Cell (MSC)-Derived Exosomes
XoGlo® is a sterile suspension of purified mesenchymal stem cell (MSC)-derived exosomes. This cosmetic product contains a multitude of growth factors, which are involved in skin repair, beautification and regeneration.
XoGlo® is a cell-free isolate of MSC exosomes that is produced using growth media that does not contain any animal or human products. Concentrated, purified MSC exosomes are sterile-filtered and re-suspended in saline. To produce these exosomes, mesenchymal stem cells are sourced from rigorously screened, voluntary donors after healthy, full-term C-section deliveries. The product undergoes thorough screening, sterility and endotoxin testing before shipment. The physiologic effects of the exosomal growth factors in XoGlo® could be studied to enhance healing of acute and chronic wounds, restore collagen in aging and damaged skin and reduce inflammation to improve the appearance of scars.
Amniotic Fluid Exosomes
Amnio2X® is a sterile-filtered amniotic fluid-derived exosome product. Amniotic fluid contains billions of exosomes. Twice the growth factors, twice the potential healing of un-processed amniotic fluid.
Amnio2X® is sourced from rigorously screened, voluntary donors after healthy, full-term C-section deliveries. The product undergoes thorough screening, sterility and endotoxin testing before shipment. Note: This is not an isolated exosome product. For isolated exosomes, see our XoGlo® exosome product.
Clinical Research Exosomes
Pharmaceutical-Grade MSC Exosomes
Kimera Labs manufactures sterile, pharmaceutical-grade mesenchymal stem cell exosomes for future IRB-approved clinical research.
Knowing the therapeutic potential of MSC exosomes for the treatment of autoimmune, inflammatory, degenerative, metabolic, and malignant conditions, as well as traumatic injuries, Kimera Labs produces purified, mesenchymal stem cell exosomes for its own scientific research, as well as future academic and professional, clinical research. Kimera Labs is actively involved in pre-clinical biopharmaceutical research directed toward the development of future clinical treatments and cures. (Sample product image is not indicative of clinical research exosome labeling)
Using Kimera Labs Products
All of the Kimera Labs exosome products (XoGlo®, Amnio2X, Clinical Research Exosomes) are cryopreserved at -80•C and shipped frozen with dry ice in an insulated container. The product should be stored frozen in a standard freezer (-20•C) after delivery.
Kimera Labs products may be stored frozen for more than 6 months before use. Do NOT store these products in liquid nitrogen. Prior to using these products, they should be thawed at room temperature for 15 minutes. Do NOT agitate or heat these products while thawing. Amniotic fluid products, such as Amnio2X, should NEVER be injected intravenously as this can cause life-threatening complications in the same way as amniotic fluid embolism. Kimera Labs uses a proprietary isolation and purification process to produce MSC exosome products from pure, isolated mesenchymal stem cell cultures. Isolation of MSC exosomes from isolated MSC cultures provides a degree of exosome purity and consistency that could enable a broad scope of clinical investigation, unlike exosome products prepared by directly processing tissue, which are very likely to contain other particulate biologic material that carries a significant risk for complications in human clinical research.