Purified Mesenchymal Stem Cell (MSC) Exosomes

Pharmaceutical Grade MSC Exosomes for Clinical Research



Purified Mesenchymal Stem Cell (MSC)-Derived Exosomes

XoGlo® is a sterile suspension of isolated mesenchymal stem cell (MSC)-derived extracellular vesicles.

This cell-free isolate of exosomes is produced by a master cell line of neonatal mesenchymal stem cells originally isolated from rigorously screened placental tissue donated after healthy C-section delivery. Stem cells from this master cell line are freshly cultured using xeno-free chemically defined culture media that does not contain any animal or human serum. These MSC Exosomes are isolated from conditioned media after separation from the parent cells and then suspended in sterile saline. This product undergoes thorough screening, sterility and endotoxin testing before being released from quarantine.

Clinical Research Exosomes

Pharmaceutical-Grade MSC Exosomes

Kimera Labs® manufactures sterile suspensions of isolated, neonatal, mesenchymal stem cell exosomes for IRB-approved preclinical research and development of clinical investigational study.

Knowing the therapeutic potential of MSC exosomes for autoimmune, inflammatory, degenerative, metabolic, and malignant conditions, as well as traumatic injuries, Kimera Labs® produces isolated MSC exosomes for scientific research and future academic and professional clinical research. Kimera Labs® is actively involved in preclinical research directed toward the development of exosome biopharmaceuticals for future clinical therapy. (Sample product image is not indicative of clinical research exosome labeling)

Using Kimera Labs Products

All of the Kimera Labs exosome products (XoGlo® and Clinical Research Exosomes) are cryopreserved at -80•C and shipped frozen with dry ice in an insulated container. The product should be stored frozen in a standard freezer (-20•C) after delivery.

Kimera Labs® exosome products may be stored frozen for up to one year. These products should not be stored in liquid nitrogen. Exosome products may be thawed at room temperature for 15 minutes. Agitation of the product or heating of the products should be avoided. Kimera Labs uses a proprietary isolation and purification process to produce MSC exosome products from pure, isolated mesenchymal stem cell cultures. Isolation of MSC exosomes and precise exosome analysis provides a degree of exosome purity and consistency that could enable a broad scope of clinical investigation. Production of exosomes from isolated MSC cultures derived from a master cell line reduces the risk of pathogen or particulate contamination associated with exosomes produced by direct tissue processing. Sterility and endotoxin testing of each lot of Kimera® exosomes is performed to ensure the purity of these products.